Epigenetic Testing for Personalized Health: The Missing Clues in Your Diet, Detox, and Stress Response

I am thrilled to bring you this week’s guest, Becca Roses, the founder of MindBodyGenes and a Certified Epigenetics Human Performance Coach. Becca has dedicated her career to helping people stop guessing with their health by translating complex genetic blueprints into practical, personalized wellness strategies. She understands that your genes are not your destiny, but rather a roadmap that can guide you toward optimal health when you know how to read the signs.

This episode is deeply personal for me. When I was studying functional medicine twenty years ago, epigenetics was already becoming an important part of the conversation. I remember doing my own genetic testing early on and discovering my MTHFR mutations and my challenges with the GSTM1 detox gene. I have also navigated testing for my daughter to ensure we support her methylation pathways correctly from a young age. Hearing Becca explain how our daily inputs influence our genetic expression reinforces everything I have taught about taking back your health. If you have ever felt like you are doing everything right but still struggling with stubborn symptoms, chronic stress, or mystery food reactions, I made this episode for you.

Becca also shares her own powerful story of being diagnosed with Hashimoto’s in 2020 after a demanding career and three children. She actually used many of my supplements, including Leaky Gut Revive, during her healing journey. However, discovering epigenetics was the missing piece that allowed her to put her autoimmune condition into remission. That realization transformed her life and led her to create the MindBodyGenes Blueprint and the Gene Queen Certification to train other practitioners in a human-first, pattern-based approach to DNA interpretation.

What I Cover In This Episode

Why Single-Gene Protocols Miss the Mark

We have all heard the buzzwords around specific genes like MTHFR, and it is easy to latch onto a single SNP and build an entire protocol around it. Becca explains why this approach is fundamentally flawed. Your body does not operate on a single gene; it works in a symphony of patterns. Hyper-focusing on one genetic variant without considering the broader picture can actually backfire. Becca walks us through how genes like MTHFR interact with COMT, AHCY, and others to create a complete metabolic picture. She emphasizes that your environment, your food, your movement, and your relationships are the inputs that pull the trigger on the genetic gun you were born with.

The COMT Spectrum and Your Stress Response

If you are a woman navigating the stress of career, family, and daily life, you need to understand your COMT gene. Becca breaks down the COMT spectrum into three categories: the warrior, the worrier, and the mediator. This gene can influence how quickly you clear stress chemicals and catecholamines from your system. I am a classic worrier with a slower clearance rate, which means I have to be incredibly mindful of my stress and caffeine intake. Becca explains how understanding where you fall on this spectrum can completely change how you manage stress, mood, and resilience, especially as we age and navigate autoimmune challenges.

The Hidden Detox Bottleneck

I have always known I am not a great detoxifier, and Becca’s explanation of the detox pathways sheds so much light on why guided genetic interpretation is crucial. She breaks down the detox process into phases. Many people have a very fast Phase 1, meaning they break down toxins quickly, but a very slow Phase 2, meaning they cannot clear those toxins efficiently. This creates a massive bottleneck in the body. Becca also highlights the often-overlooked Phase 3, which involves estrogen metabolite elimination. Understanding these bottlenecks allows you to support your body exactly where it needs help rather than relying on generic detox protocols that might not serve your specific biology.

Personalizing Nutrition and the Glutamate Seesaw

Have you ever tried a strict low-carb diet only to feel completely depleted and exhausted? Becca explains that your genes hold the answer. She discusses the PLIN1 gene and why some people may function better with more complex carbohydrates for energy and metabolic support. We also dive into the FTO and ELOVL genes to understand how your body processes fats and omegas. Perhaps most fascinating is her breakdown of the GAD1 gene and the glutamate to GABA seesaw. For children and adults dealing with focus issues, anxiety, or feeling constantly wired, understanding how efficiently they process excitatory glutamate into calming GABA can be life-changing.

The Mind in MindBodyGenes

You cannot separate the mind from the body when it comes to genetic expression. Becca emphasizes that the state your nervous system lives in absolutely matters. Becca explains that years of chronic stress and feeling unsafe can influence inflammation, hormones, detox pathways, and how the body expresses its genetic tendencies. This is why her coaching approach is deeply nervous system-aware. She also shares details about her self-paced Gene Queen Certification, designed to help practitioners integrate this comprehensive, pattern-based genetic testing into their own practices to better serve their clients.

About Becca Roses

Becca Roses is the Founder of MindBodyGenes and a Certified Epigenetics Human Performance Coach. She helps clients translate their genetic blueprints into personalized, practical wellness strategies across nutrition, detox, sleep, exercise, hormones, and nervous system support. After navigating her own Hashimoto’s journey and seeing the power of pattern-based genetics in her life and work with clients, Becca created the MindBodyGenes Blueprint and the Gene Queen Certification to train coaches and practitioners to interpret DNA with a human-first, epigenetics-driven approach.

Resources and People Mentioned:

• MindBodyGenes Genetic Blueprint and guided interpretation
• Gene Queen Certification for coaches and practitioners
• Existing raw genetic data from 23andMe and AncestryDNA

Connect with Dr. Myers:

• Website: https://www.dramymyers.com/
• Dr. Myers’ Inner Circle: https://www.drmyersinnercircle.com
• Newsletter: https://dramymyers.com/
• Facebook: https://www.facebook.com/dramymyers
• Instagram: https://www.instagram.com/dramymyers

Connect with Becca Roses:

• Website: https://mindbodygenes.com/
• Instagram: https://www.instagram.com/mindbodygenes
• Email: becca@mindbodygenes.com

Episode Timestamps

• 00:00 How your nervous system shapes gene expression
• 01:39 Becca’s Hashimoto’s story and finding the missing piece
• 07:33 Epigenetics explained and the inputs that influence your genes
• 08:40 SNPs 101 and why single-gene protocols miss the mark
• 11:11 COMT: warrior, worrier, mediator, and your stress response
• 13:20 Detox genes, glutathione, and guided interpretation
• 17:38 Inside the MindBodyGenes Blueprint and 90-minute deep dive
• 21:57 Should you test your children’s genes?
• 26:54 Personalizing macros, fats, and neurotransmitter support
• 31:02 Thousands of SNPs and more than 70,000 possible combinations
• 34:36 The detox bottleneck: Phase 1, Phase 2, and Phase 3
• 37:18 The mind in MindBodyGenes and nervous system-aware coaching
• 39:17 How the self-paced Gene Queen Certification works
• 41:12 Becca’s three ways to take back your health
• 42:26 Where to connect with Becca